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Home > Products >  Loxo 101 /Larotrectinib/ Intermediates

Loxo 101 /Larotrectinib/ Intermediates CAS NO.2135871-21-3

  • FOB Price: USD 10 /Metric Ton Get Latest Price
  • Min.Order: 1 Gram
  • Payment Terms: L/C,D/P,T/T,Western Union
  • Available Specifications:

    99%(1-10)Metric Ton99%(1-100)Metric Ton

  • Product Details

Keywords

  • ARRY-470
  • sell GSK1349572
  • Larotrectinib

Quick Details

  • ProName: Loxo 101 /Larotrectinib/ Intermediates
  • CasNo: 2135871-21-3
  • Molecular Formula: C20H19F2N3O5
  • Appearance: white or off-white powder
  • Application: 1051375-16-6 as chemical research
  • DeliveryTime: prompt
  • PackAge: depends on customer's requirement
  • Port: HongKong, Shenzhen, Shanghai
  • ProductionCapacity: 100 Gram/Day
  • Purity: 99%
  • Storage: keep away from heat, sparks and flames
  • Transportation: safe package by courier or by air
  • LimitNum: 1 Gram

Superiority

99% in stock

1.99% purity with low price;
2.High purity with HPLC & NMR chart;
3.Direct manufacturer;
4.specilized in hard-to-find chemicals.

LOXO-101, also known as ARRY-470, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC. LOXO-101 has IC50 values in the low nanomolar range for inhibition of all three TRK family members in binding and cellular assays, with 100x selectivity over other kinases, and has shown acceptable pharmaceutical properties and safety in nonclinical models.

Identification
Name   GSK 1349572
Synonyms   (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Molecular Formula   C20H19F2N3O5
Molecular Weight   419.38
CAS Registry Number   1051375-16-6

 

Details

Shengda Pharmaceutical Co.,Limited was established in December 2009 for Hongkong. We are a leading high-tech enterprise expertised in researching, developing and manufacturing innovative and generic drugs on anticancer, anti-HIV, anti-tumor, anti-viral, etc. Our company constantly supplies tailor-made pharmaceutical APIs, intermediates and compounds for many major pharmacy companies worldwide. Moreover, we cooperate with many famous research institutes like Sun Yat-Sen University of Medical Sciences and jointly established several accordance with GMP standard labs an production base to provide customers with high value-added pharmaceutical intermediates and excelleant R&D outsourcing services.

Below are our factory APIs&Intermediates, if you are interested in,pls contact me. We also have Lab,providing custom synthesis.
 
Identification
Name   GSK 1349572
Synonyms   (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Molecular Formula   C20H19F2N3O5
Molecular Weight   419.38
CAS Registry Number   1051375-16-6

 

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